Irregular Breathing Patterns (References)

- Updated on August 7, 2019

References and abstracts about healing powers of CO2 to restore regular breathing

Xie A, Rankin F, Rutherford R, Bradley TD. Effects of inhaled CO2 and added dead space on idiopathic central sleep apnea. J Appl Physiol. 1997 Mar;82(3):918-26.

Datta AK, Shea SA, Horner RL, Guz A. The influence of induced hypocapnia and sleep on the endogenous respiratory rhythm in humans. J Physiol. 1991;440:17-33.

Dempsey JA, Smith CA, Przybylowski T, Chenuel B, Xie A, Nakayama H, Skatrud JB. The ventilatory responsiveness to CO(2) below eupnoea as a determinant of ventilatory stability in sleep. J Physiol. 2004 Oct 1;560(Pt 1):1-11. Epub 2004 Jul 29.

Skatrud JB, Dempsey JA. Interaction of sleep state and chemical stimuli in sustaining rhythmic ventilation. J Appl Physiol. 1983 Sep;55(3):813-22.

Nakayama H, Smith CA, Rodman JR, Skatrud JB, Dempsey JA. Effect of ventilatory drive on carbon dioxide sensitivity below eupnea during sleep. Am J Respir Crit Care Med. 2002 May 1;165(9):1251-60.

Xie A, Rutherford R, Rankin F, Wong B, Bradley TD. Hypocapnia and increased ventilatory responsiveness in patients with idiopathic central sleep apnea. Am J Respir Crit Care Med. 1995 Dec;152(6 Pt 1):1950-5.

Naughton M, Benard D, Tam A, Rutherford R, Bradley TD. Role of hyperventilation in the pathogenesis of central sleep apneas in patients with congestive heart failure. Am Rev Respir Dis. 1993 Aug;148(2):330-8.

Xie A, Wong B, Phillipson EA, Slutsky AS, Bradley TD. Interaction of hyperventilation and arousal in the pathogenesis of idiopathic central sleep apnea. Am J Respir Crit Care Med. 1994 Aug;150(2):489-95.

Christon J, Carley DW, Monti D, Radulovacki M. Effects of inspired gas on sleep-related apnea in the rat. J Appl Physiol. 1996 Jun;80(6):2102-7.

Xie A, Skatrud JB, Puleo DS, Dempsey JA. Influence of arterial O2 on the susceptibility to posthyperventilation apnea during sleep. J Appl Physiol. 2006 Jan;100(1):171-7. Epub 2005 Sep 22.

Chowdhuri S, Shanidze I, Pierchala L, Belen D, Mateika JH, Badr MS. Effect of episodic hypoxia on the susceptibility to hypocapnic central apnea during NREM sleep. J Appl Physiol. 2010 Feb;108(2):369-77. Epub 2009 Nov 25.

Zhou XS, Shahabuddin S, Zahn BR, Babcock MA, Badr MS. Effect of gender on the development of hypocapnic apnea/hypopnea during NREM sleep. J Appl Physiol. 2000 Jul;89(1):192-9.

Smith CA, Nakayama H, Dempsey JA. The essential role of carotid body chemoreceptors in sleep apnea. Can J Physiol Pharmacol. 2003 Aug;81(8):774-9.

White DP. Central sleep apnea. Med Clin North Am. 1985 Nov;69(6):1205-19.

Weihu C, Jingying Y, Demin H, Yuhuan Z, Jiangyong W. End-tidal carbon dioxide concentration monitoring in obstructive sleep apnea patients. Am J Otolaryngol. 2010 May 11. [Epub ahead of print]